The influenza A virus NS 1 protein promotes efficient nuclear export of unspliced viral M 1 mRNA
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چکیده
word count: 248 20 Main text word count: 5395 21 Running title: Role of NS1 in viral mRNA nuclear export 22
منابع مشابه
Influenza A Virus NS1 Protein Promotes Efficient Nuclear Export of Unspliced Viral M1 mRNA
Influenza A virus mRNAs are transcribed by the viral RNA-dependent RNA polymerase in the cell nucleus before being exported to the cytoplasm for translation. Segment 7 produces two major transcripts: an unspliced mRNA that encodes the M1 matrix protein and a spliced transcript that encodes the M2 ion channel. Export of both mRNAs is dependent on the cellular NXF1/TAP pathway, but it is unclear ...
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